• Disease: Ehrlichiosis
  • Especially important in dogs
  • No zoonotic potential
  • Vector: Rhipicephalus sanguineus
  • Up to date not endemic in Germany
  • Direct detection methods
    • PCR (positive result indicative for acute infection)
    • Detection of morulae in monocytes (less sensitive compared to PCR and only in acute stage of infection)
  • Indirect detection methods (positive result indicative for pathogen contact in the past, paired serum samples necessary for detection of potential infection)
    • Antibody-ELISA (enzyme-linked immunosorbent assay)
    • IFAT (immunofluorescence antibody test)
  • Fever, lymphadenopathy and petechiae as the most prominent clinical signs
  • Thrombocytopenia as the most prominent hematological finding, renal failure with proteinuria possible
  • Treatment does not eliminate the pathogen

Dog (2007-2023, N = 149,859)

Timeframe

PCR

ELISA/IFAT

2020-2023

1.7%

13.1%

2016-2019

1.7%

9.9%

2012-2015

1.9%

11.9%

2007-2011

1.1%

11.3%

Cat (2012-2023, N = 715)

Timeframe

PCR

IFAT/ELISA

2020-2023

0%

23.7%

2012-2020

-

12.0%

Annual distribution of dogs tested for Ehrlichia spp. by PCR and IFAT/ELISA (2007-2019)